h�2445U0P�656RA � NP,@� 1(u #y�1�Z����z������*������U_�>��-���V}�z�>�n4hJ��0La�8�̖̆̆̆�a�:�0La��0���8b9b9b9b�ܩ�H�H�H�H�H�u��1V��. � : � :n� &&& : � 9�� endstream endobj 1549 0 obj <>stream f : � ;#� � : � :�� f�F : � :�� endstream endobj 1550 0 obj <>stream �� nP,@� 9�� *� f&& : � :P� endstream endobj 1521 0 obj <>stream �f : � 9�� ��F : � 9D� F�F : � 9�� h�2421S0P���4RA h�2444Q0P�663RA endstream endobj 1639 0 obj <>stream �& : � :/� endstream endobj 1553 0 obj <>stream & : � 9�� endstream endobj 1504 0 obj <>stream : � :�� h�2442R0P�6��RA ff : � :�� h�2446P0P�616RA endstream endobj 1506 0 obj <>stream h�2422S0P��04RA �&& : � :�� he electronic version may be found on the Oice of . �F : � :�� endstream endobj 1685 0 obj <>stream � : � :�� endstream endobj 1531 0 obj <>stream F`nP,@� :�� endstream endobj 1538 0 obj <>stream Care and Management of Laboratory Animals: Laboratory animals in most countries are protected by the Law “Cruelty to Animals Act”. endstream endobj 1520 0 obj <>stream & * � 0ac ��F : � 9D� h�2407T0P�6�4RA endstream endobj 1475 0 obj <>stream f& : � :�� endstream endobj 1651 0 obj <>stream h�244�P0P�613RA Laboratory Animal Welfare (OLAW) website at OLAW.nih.gov and includes . endstream endobj 1467 0 obj <>stream h�2445Q0P�652RA h�2444R0P�66�RA �&& : � :_� endstream endobj 1489 0 obj <>stream h�2422P0P�6�4RA endstream endobj 1571 0 obj <>stream Lab cleanliness is one of the easiest, most affordable and most obvious ways to keep your lab in great shape but surprisingly is often overlooked. endstream endobj 1583 0 obj <>stream h�2422Q0P��00RA It is imperative to all of us to look in the welfare of these animals. Introduction. endstream endobj 1663 0 obj <>stream endstream endobj 1568 0 obj <>stream endstream endobj 1476 0 obj <>stream &F : � 9�� h�24��T0P�623RA endstream endobj 1537 0 obj <>stream endstream endobj 1662 0 obj <>stream This table provides necessary data for breeding colonies: Item Rat Mouse Breeding Age Male Female. The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. F�F : � :_� endstream endobj 1567 0 obj <>stream endstream endobj 1540 0 obj <>stream h�240�P0P�63�A endstream endobj 1625 0 obj <>stream �� nP,@� :>� h�2440P0P�664RA 1464 0 obj <>stream This is to ensure that we give you the best experience possible. endstream endobj 1523 0 obj <>stream �& : � 9z� endstream endobj 1615 0 obj <>stream �& : � 9�� �f& : � 9�� endstream endobj 1614 0 obj <>stream h�2441T0P�617RA endstream endobj 1518 0 obj <>stream h�2444V0P�66QA endstream endobj 1711 0 obj <>stream h�240�T0P�640RA ��F : � :P� && : � : � h�2426S0P��05RA endstream endobj 1643 0 obj <>stream h�2401S0P��4�A endstream endobj 1636 0 obj <>stream endstream endobj 1665 0 obj <>stream This PDF is available to Subscribers Only. h�2442U0P�614RA �F * � /�Z h�2446W0P�61�RA ��f : � : � h�244�T0P�6�0RA � nP,@� :�� endstream endobj 1487 0 obj <>stream f� nP,@� :�� �� nP,@� 9�� � : � 5�� �&& : � 9�� endstream endobj 1544 0 obj <>stream h�24�4R0P�63�RA h�242�P0P��03RA h�2424R0P�67�RA h�2425V0P��4QA h�2401T0P�67�A h�24�0Q0P�621RA h�2447P0P�6�4RA endstream endobj 1619 0 obj <>stream h�244�T0P�613RA �& : � :M� Continuing to use www.cabdirect.org h�2406Q0P�61�A endstream endobj 1676 0 obj <>stream History of animal experimentation Humans have been using animals for a very long time, initially for food, for transport and for companionship. h�2405P0P�644RA You can now claim your publications on CAB Direct with your ORCID iD! [Washington] National Institutes of Health [For sale by the Supt. f * � 14u h�2421W0P����RA endstream endobj 1656 0 obj <>stream endstream endobj 1609 0 obj <>stream NTU-ARF-SOP-10: SOP for Change of Compressed Gas Cylinders 46 NTU-ARF-SOP-11: SOP for Receiving Bedding and Diet 49. �F : � :A� f : � :G� ��f : � 9;� ��f : � :�� h�24��P0P�670RA h�24�0Q0P�631RA ƆF : � 8�� endstream endobj 1631 0 obj <>stream These guidelines are a consensus of views obtained from scientists and consultants working in academic and industrial spheres as well as from societies and associations that have a direct interest. Institutional Animal Care And Use Committee (IACUC): a committee constituted in accordance with the terms of reference and membership laid down in the Code. endstream endobj 1515 0 obj <>stream endstream endobj 1488 0 obj <>stream Carry out a weekly deep clean of all equipment 3. h�2423P0P��45RA h�2420T0P�674RA f& : � :h� �� * � 0\ ��F : � :Y� h�2423V0P��SA #{�uK�F���U�sf��΄��֫� �� *d����C��ѯ�;�٘��~掳�8)㤌�2NJ>����g�y&�g��~.h\�_�0��ɝ�]��U��ը������C���ò�'��!�A�a$ם�Q��@T *eu �F#�[�! The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities—a resource of proven value, now updated and expanded. � NP,@� 0�l endstream endobj 1635 0 obj <>stream ��F : � :�� h�2444S0P�667RA &�F : � 9\� endstream endobj 1648 0 obj <>stream endstream endobj 1703 0 obj <>stream � : � ;� Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. �F : � 9�� ƦF : � 9� This section includes descriptions of each of 7 different components that collectively constitute a program of animal care and use. endstream endobj 1657 0 obj <>stream h�24�4V0P�6� QA endstream endobj 1674 0 obj <>stream F& : � :P� h�2421T0P��07RA �F : � :Y� & : � :�� endstream endobj 1668 0 obj <>stream �� nP,@� :G� �F& : � 9�� h�244�P0P�612RA : � : � endstream endobj 1596 0 obj <>stream endstream endobj 1595 0 obj <>stream � : � ;� �f * � 0�l endstream endobj 1686 0 obj <>stream h�24��P0P�660RA �f : � 9�� ��F : � 9�� h�2441R0P�61�RA �f : � :g� endstream endobj 1683 0 obj <>stream endstream endobj 1502 0 obj <>stream endstream endobj 1707 0 obj <>stream endstream endobj 1555 0 obj <>stream h�2425P0P��44RA ��f : � 9�� �F : � 9�� F�F : � 9\� endstream endobj 1560 0 obj <>stream h�2403S0P�647RA endstream endobj 1496 0 obj <>stream h�242�P0P�671RA FF : � :e� endstream endobj 1572 0 obj <>stream endstream endobj 1600 0 obj <>stream h�242�T0P�671RA h�2422T0P�6�4RA endstream endobj 1519 0 obj <>stream CAB Direct is the most thorough and extensive source of reference in the applied life sciences, &�F : � 9�� h�2407Q0P�620RA h�2406U0P�65�A The 3A caretaker is responsible for maintenance of rodent colonies to be bred for use by principal investigators. endstream endobj 1594 0 obj <>stream h�2405S0P�646RA endstream endobj 1664 0 obj <>stream �& : � ;;� ��F : � :)� h�240�P0P�641RA endstream endobj 1587 0 obj <>stream endstream endobj 1526 0 obj <>stream The Welfare of Laboratory Animals PDF.. endstream endobj 1680 0 obj <>stream � : � :�� � : � ;\� h�24�0R0P�62�RA F : � :�� endstream endobj 1709 0 obj <>stream endstream endobj 1493 0 obj <>stream h�2424V0P�67QA �F : � 9�� h�244�T0P�661RA endstream endobj 1691 0 obj <>stream �& : � 9�� h�2403Q0P�643RA h�24�4P0P�637RA f : � :�� endstream endobj 1604 0 obj <>stream h�244�T0P�612RA fF& : � :w� The methods and elementary precautions described so briefly in this paper are well known to workers who have had to learn by experience; it is well therefore that such knowledge should be gathered into one paper and made available to those who have to look after laboratory animals and insect cultures. � nP,@� ;� &�f : � :� h�2440W0P�66�RA h�2425U0P��46RA h�2401R0P�6��A h�2420Q0P�672RA endstream endobj 1575 0 obj <>stream ��F : � 9�� h�24�4W0P�6��RA h�2421Q0P���0RA h�2420V0P�67QA �f : � :v� h�2423Q0P��43RA endstream endobj 1528 0 obj <>stream h�2440T0P�664RA h�2424W0P�67�RA �f : � :)� pursuing certification with the Canadian Association for Laboratory Animal Science (CALAS‐ACSAL) as an RLAT or RMLAT, or equivalent levels of education, with similar organizations. � : � :�� h�2442V0P�61 QA ƖF : � 9�� Carry out a daily wipe down of all equipment exteriors 2. Print. h�2442W0P�61�RA h�2441U0P�6�4RA & : � :A� h�2425T0P��44RA h�2444T0P�665RA endstream endobj 1695 0 obj <>stream Off] 1968 (OCoLC)607711467: Document Type: Book: All Authors / Contributors: h�2426U0P��05RA h�242�T0P��03RA h�2447W0P�63�RA fF : � :�� The Eighth Edition of the Guide for the Care and Use of Laboratory Animals (NRC 2011) is available for download — click here to download a PDF of the Guide. F : � : � endstream endobj 1492 0 obj <>stream endstream endobj 1584 0 obj <>stream endstream endobj 1682 0 obj <>stream h�24�0R0P�63�RA h�2442P0P�6�4RA endstream endobj 1623 0 obj <>stream h�2447T0P�6�4RA h�24�0P0P�626RA h�240�T0P�63�A endstream endobj 1599 0 obj <>stream h�2443T0P�655RA h�2420S0P�676RA �&& : � 9�� ��F : � 9�� endstream endobj 1655 0 obj <>stream F& : � :>� endstream endobj 1466 0 obj <>stream �� nP,@� :� h�242�T0P���0RA endstream endobj 1705 0 obj <>stream endstream endobj 1610 0 obj <>stream The course will cover the basic of how to manage animal facility, routine care and husbandry practices of animals, experimental procedures and techniques, quality control procedures etc. ��F : � 9k� endstream endobj 1618 0 obj <>stream endstream endobj 1472 0 obj <>stream h�2446S0P�615RA h�2424P0P�675RA F� nP,@� 9�� The two most important aspects of maintaining and/or monitoring a breeding colony are knowledge of the animals’ breeding cycles and accurate record keeping. Handling of experimental animal Mr. Subhash Lal Karn Dept. �F : � :/� F�F : � 9�� endstream endobj 1629 0 obj <>stream endstream endobj 1650 0 obj <>stream endstream endobj 1678 0 obj <>stream endstream endobj 1508 0 obj <>stream �� nP,@� :�� h�2443U0P�657RA h�2403R0P�64�RA endstream endobj 1522 0 obj <>stream Carry out a regular deep clean of microscopes using a 70:30 mixture of ether and alcohol – this ensures that they are sufficiently clean to yield most accurate re… �& : � :&� &� nP,@� :�� h�2443Q0P�653RA endstream endobj 1634 0 obj <>stream h�242�T0P�6�0RA �& : � :�� endstream endobj 1611 0 obj <>stream endstream endobj 1581 0 obj <>stream CAB Direct endstream endobj 1577 0 obj <>stream endstream endobj 1500 0 obj <>stream h�2422U0P��04RA && : � :)� endstream endobj 1684 0 obj <>stream endstream endobj 1692 0 obj <>stream h�2403U0P�647RA h�2407U0P�624RA �F : � 9k� Like most websites we use cookies. h�2405V0P�64QA ��F : � 9�� �F& : � 9�� endstream endobj 1603 0 obj <>stream endstream endobj 1627 0 obj <>stream h�24�4S0P�6�4RA h�242�P0P�6�0RA h�2440S0P�666RA h�24�4U0P�6�4RA h�2445V0P�65QA F&& : � 9�� ��F : � :)� h�24�4Q0P�6�0RA h�2425R0P��4�RA & : � :�� &� nP,@� 9�� endstream endobj 1478 0 obj <>stream �& : � :�� h�2445W0P�65�RA endstream endobj 1706 0 obj <>stream The solicitation provided for a best value evaluation based on technical, past performance and price factors. h�240�T0P�6�0RA �F * � 0@c h�240�P0P�6�0RA f`nP,@� ;;� Ff& : � :n� f�F : � 9�� endstream endobj 1641 0 obj <>stream endstream endobj 1590 0 obj <>stream F�F : � 9�� h�2447S0P�634RA h�24�4T0P�627RA endstream endobj 1670 0 obj <>stream Introduction •Healthy and well being of lab. D%�E#F#���r�@T *�*�S)�F h�2443S0P�657RA Ɩf : � 9�� F& : � :G� endstream endobj 1529 0 obj <>stream h�242�P0P���0RA endstream endobj 1704 0 obj <>stream &f : � :_� �f * � 07c �& : � :�� h�24�4S0P�6�4RA There are over 13,717,000 records available in CAB Direct | Last updated on January 26, 2021. �f& : � :� Care and Maintenance of Laboratory Animals. �& : � : � f�F : � :h� endstream endobj 1509 0 obj <>stream endstream endobj 1632 0 obj <>stream endstream endobj 1605 0 obj <>stream �F : � 9D� f� nP,@� :_� h�2402U0P�64�A h�2405Q0P�642RA h�2403P0P�645RA endstream endobj 1546 0 obj <>stream endstream endobj 1645 0 obj <>stream endstream endobj 1646 0 obj <>stream & : � :�� � : � ;2� endstream endobj 1525 0 obj <>stream �& : � :� h�2446T0P�616RA endstream endobj 1497 0 obj <>stream Introduction: Laboratory animals such as mice, rats and guinea pigs are most commonly used experimental animals for study of different biological activities in health and disease. �� nP,@� :�� endstream endobj 1617 0 obj <>stream h�2420P0P�674RA session so others can sign in. h�2406P0P�66�A �f : � :� endstream endobj 1479 0 obj <>stream h�2427P0P���4RA h�244�T0P�6�0RA f& * � 0�l h�2405T0P�644RA �o�٩{�C���'-)_��TL끦7N� �R� Ɔf : � 9� f& : � :�� Find out more about this exciting new development, Using our new visualization tools you can, Using our new highlighting and annotation tool you can, remove selected records that are not saved in My CABI, sign you out of your h�2442T0P�6�4RA h�2426W0P��0�RA * *Please note that the 2011 Guide is copyrighted b h�2445S0P�656RA FF : � :� endstream endobj 1638 0 obj <>stream : � :�� &�F : � 95� endstream endobj 1552 0 obj <>stream ��F : � :�� h�2426T0P��06RA h�2406T0P�66�A endstream endobj 1700 0 obj <>stream && * � 0Lc h�24�0T0P�636RA Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. h�24�4U0P�6�4RA h�24�0S0P�625RA h�2423S0P��47RA endstream endobj 1582 0 obj <>stream h�2443W0P�65�RA �F& : � :A� h�244�T0P�632RA h�2420R0P�67�RA h�2447R0P�6��RA With the worldwide increase in biotechnology, more and more researchers are required to use animals for research. h�2423R0P��4�RA h�2423U0P��47RA �f : � 9�� �& : � :�� F& : � 9k� h�244�P0P�651RA h�240�P0P�62�A endstream endobj 1681 0 obj <>stream �F& : � 9,� h�24�0S0P�635RA h�242�T0P��02RA ��f : � 9�� �F : � 9�� h�2441P0P�617RA endstream endobj 1675 0 obj <>stream endstream endobj 1607 0 obj <>stream endstream endobj 1673 0 obj <>stream f& : � :�� Public Health Service Policy on Humane Care and Use of Laboratory Animals I. endstream endobj 1667 0 obj <>stream endstream endobj 1710 0 obj <>stream h�2424U0P�677RA �&& : � :8� endstream endobj 1547 0 obj <>stream � : � ;-� and Human Services, Centers for Disease Control and Prevention (CDC), for the care and maintenance of laboratory animals (used for research) at the Chamblee and Lawrenceville animal care facilities. �& : � :w� endstream endobj 1505 0 obj <>stream endstream endobj 1606 0 obj <>stream �F : � :�� endstream endobj 1654 0 obj <>stream f�f : � :8� h�2407R0P�6��RA h�24�4R0P�62�RA & * � 0�l LABORATORY ANIMALS FOR THE CARE AND USE OF Eighth Edition Committee for the Update of the Guide for the Care . endstream endobj 1532 0 obj <>stream NOTICE: The project that is the subject of this report was approved by the … &f& : � :G� h�24�4Q0P�6�0RA Guide to the Care and Use of Experimental Animals Volume 1, 2nd Edition Canadian Council on Animal Care Conseil canadien de protection des animaux Sections of this document that have been revised are replaced by links to the relevant F : � :h� hެ�[k�@���>�H�[.D0jj����� �E���ݍ����/��9�|�f#�(a1��!�纠�s|����9�L����8M >�mq��������x>��:հ������舧y��Ĵ��e6!�Q�$��!D�BB�B]����Q}y�d^��+��~���;�NK봌��:FS���� � $ �H 5���L��Nz��VA��4���������J�lMzZ�W;o��m�����9��vz r��پ�݌`�Y���hg#݀���Jb��1��w�%� zs�I endstream endobj 1580 0 obj <>stream h�2401Q0P��0�A h�244�P0P�661RA h�2403V0P�6SA endstream endobj 1579 0 obj <>stream f�F : � 9�� FF& : � : � h�2441Q0P�6�0RA ff : � ;J� �f : � 9�� h�2446Q0P�611RA endstream endobj 1473 0 obj <>stream Ʀf : � 9�� endstream endobj 1679 0 obj <>stream : � :Y� endstream endobj 1688 0 obj <>stream �& : � :h� endstream endobj 1591 0 obj <>stream endstream endobj 1565 0 obj <>stream These animal can serve as a model for a human being in all those functions in which there is a considerable degree a convenient, single point of access to all of your CABI database subscriptions. endstream endobj 1622 0 obj <>stream Animal welfare is attracting increasing interest worldwide, but particularly from those in developed countries, who now have the knowledge and resources to be able to offer the best management systems for their farm animals, as well as potentially being able to offer plentiful resources for companion, zoo and laboratory animals. ��f : � :)� endstream endobj 1530 0 obj <>stream �F : � :� endstream endobj 1465 0 obj <>stream �& : � :V� & : � :8� F& * � 0mc ��f : � :�� h�2447U0P�634RA � nP,@� :8� endstream endobj 1696 0 obj <>stream endstream endobj 1533 0 obj <>stream h�24�0T0P�626RA && : � 9�� endstream endobj 1672 0 obj <>stream Guide for laboratory animal facilities and care. � : � :�� endstream endobj 1573 0 obj <>stream If you would like to, you can learn more about the cookies we use. h�2443P0P�655RA Maintence and breeding of laboratory animals 1. h�244�T0P�651RA h�2441S0P�6�4RA of Docs., U.S. Govt. endstream endobj 1551 0 obj <>stream �f : � :�� F * � 0�l endstream endobj 1477 0 obj <>stream endstream endobj 1642 0 obj <>stream Laboratory animal research remains a very important part of basic research and drug development. endstream endobj 1543 0 obj <>stream endstream endobj 1593 0 obj <>stream h�2442Q0P�610RA endstream endobj 1574 0 obj <>stream f�F : � :A� endstream endobj 1677 0 obj <>stream endstream endobj 1666 0 obj <>stream endstream endobj 1649 0 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View Article Abstract & Purchase Options. endstream endobj 1536 0 obj <>stream &�f : � 9�� THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001. h�24�0U0P�625RA h�244�P0P�632RA h�2425S0P��46RA Ff : � :�� is intended to assure quality maintenance and safety of animals used in laboratory studies while conducting biomedical and behavioral research and testing of products. h�2407V0P�62 QA f : � :�� endstream endobj 1503 0 obj <>stream endstream endobj 1621 0 obj <>stream h�2442S0P�614RA of Microbiology U.C.M.S. �f : � 9�� �& : � ;D� endstream endobj 1658 0 obj <>stream hޜ���%5F_�o0��sYZmBH�Vd� �"�.o�}}j�Xt{��;�.�|_�=]���u��q�H�hS�;�f�w�-NN�������d��;X���ٚQt��Έ�oҺ����m�u�����{5����ʊ����Ѥg�(�h<1�bw!����~�{��� �&���65�����ҽR��=�Z�1��!���������7?���&{P^_�|��o��˟^?��w��u$�p� � h�242�P0P��41RA �� nP,@� :�� Extensive online help - available wherever you are in CAB Direct. h�2420W0P�67�RA h�2445R0P�65�RA endstream endobj 1694 0 obj <>stream h�242�P0P��02RA endstream endobj 1501 0 obj <>stream endstream endobj 1557 0 obj <>stream ��F : � 8�� h�244�P0P�6�0RA Care and Use of Laboratory Animals (Policy) is available in both printed and electronic formats. endstream endobj 1482 0 obj <>stream endstream endobj 1484 0 obj <>stream endstream endobj 1653 0 obj <>stream h�24��T0P�633RA h�,�Mk�0����%�r�d�R�;�viG�/(=�L�fN\�����yīW"!K@B �j��K�}Q)pk���9B�T�̳�d��r��@.��}���3*)9 5FM�d+�Yw{���h�gn�@Oc�C;�1�돷�^�ә��'�:��w>t�%�u�&�F�l��[� ���}�� endstream endobj 1534 0 obj <>stream endstream endobj 1608 0 obj <>stream and Use of Laboratory Animals Institute for Laboratory Animal Research . h�24�0W0P�62�RA endstream endobj 1558 0 obj <>stream h�24�4T0P�637RA F& : � 9�� ��F : � :2� endstream endobj 1628 0 obj <>stream h�2447Q0P�630RA �f : � :&� endstream endobj 1474 0 obj <>stream h�2405U0P�646RA f& : � 9�� F : � :_� &� nP,@� :/� ��F : � 9�� h�2425Q0P��42RA endstream endobj 1511 0 obj <>stream f�f : � :�� �& : � :�� && : � :� endstream endobj 1652 0 obj <>stream &�F : � :8� �f : � ;� �� nP,@� ;,� We deny the protest. & : � 9�� Guide for the Care and Use of Laboratory Animals: Eighth Edition THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001 NOTICE: The project that is the subject of this report was approved by the Govern- ing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineer-ing, … To all of us to look in the Welfare of these animals with worldwide! 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